The aim of the PhD is to test the hypothesis that certain environmental factors are needed to precipitate the rare kidney disease atypical haemolytic ureamic syndrome (aHUS) using a unique comparative model. You will be part of the National Renal Complement Therapeutics centre; based in the Complement Therapeutics Research Group’s and the new Immunology, Inflammation and Immunotherapy theme laboratories.
We will measure kidney function, in the model compared to controls, during infectious responses or immunological stress or autoimmune diseases via biochemistry and immune-phenotyping techniques (ELISA, Flow cytometry and Immunohistochemistry / immunofluorescence). This research will provide information that can be used to improve patient care/management and provide the best model for the pre-clinical testing anti-complement therapeutics.
- Number of awards: 1
- Start date and duration: 2 October 2017 for 3 years (PhD only).
- Application closing date: 5 June 2017 at 5.00pm.
- Sponsor: Kidney Research UK
- Name of supervisor(s): Dr Kevin J Marchbank and Professor David Kavanagh, Institute of Cellular Medicine
Value of award
100% of UK/EU tuition fees paid and annual living expenses of £14,057 (full award). Successful international candidates will be required to make up the difference between the UK/EU fees and international fees.
Eligibility Criteria
You must have, or expect to achieve, at least a 2:1 in a Biological Sciences (Immunology and Biochemistry). Knowledge of comparative modelling and Immunology would be helpful for progression in the project.
This award is available to UK/EU and international applicants. If English is not your first language, you must have IELTS 7 with at least 6.5 in the written component, or equivalent.
For further information, please refer to http://www.kidneyresearchuk.org/file/research/Regulations-and-Conditions-2016.pdf.
How to apply
You must apply through the University’s online postgraduate application system. To do this please ‘Create a new account’.
Only mandatory fields need to be completed. However, you will need to include the following information:
- insert the programme code 8300F in the programme of study section
- select ‘PhD in the Faculty of Medical Sciences – cellular medicine ‘ as the programme of study
- insert the studentship code CL096 in the studentship/partnership reference field
- attach a covering letter and CV. The covering letter must state the title of the studentship, quote the studentship reference code CL096 and state how your interests and experience relate to the project
- attach degree transcripts and certificates and, if English is not your first language, a copy of your English language qualifications.
Contact
For further information, please contact:
Dr Kevin J Marchbank, Institute of Cellular Medicine
Email: Kevin.Marchbank@ncl.ac.uk
Telephone: +44 191 208 5998
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